Ultrasound based method for one-pot synthesis of substituted imidazoles using SiO2-OSbCl2 as highly effective and reusable catalyst

نویسندگان

  • Javad Safari Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R., Iran.
  • Simin Naseh Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R., Iran.
  • Zahra Akbari Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R., Iran.
  • Zohre Zarnegar Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, I.R., Iran.
چکیده مقاله:

A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicability to various substrates make this method an interesting alternative to previously applied procedures. From the environmental standpoint, this eco-friendly green catalyst is stable, highly active, easy to prepare and handle.

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ultrasound based method for one-pot synthesis of substituted imidazoles using sio2-osbcl2 as highly effective and reusable catalyst

a simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (sio2-osbcl2) as a catalyst in ethanol at moderate temperature. operational simplicity, practicability and applicabi...

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عنوان ژورنال

دوره 4  شماره 3

صفحات  125- 132

تاریخ انتشار 2014-09-01

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